Ascorbic Acid and the Common Cold Analysis of controlled studies shows ivith statistical significance that this vitamin has protective power

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  • Linus Pauling
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The significance of the evidence about ascorbic acid and the common cold.

Only four independent double-blind studies have been reported of the effect of ascorbic acid regularly ingested in daily amounts more than 100 mg, in comparison with a placebo, in decreasing the incidence and integrated morbidity of the common cold for subjects exposed to cold viruses in the ordinary way and without colds when the test period began. A statistical analysis of these four studies ...

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To the Editor.—My book, Vitamin C and the Common Cold was reviewed in THE JOURNAL by Franklin C. Bing (215:1506, 1971). I do not object to the expression by the reviewer of his opinions, However, it is essential that the several untrue and thoroughly misleading statements that he makes be corrected. I do not state that ascorbic acid is a completely harmless chemical. I describe it as natural, e...

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Does vitamin C alleviate the symptoms of the common cold?--a review of current evidence.

Since 1971, 21 placebo-controlled studies have been made to establish whether vitamin C at a dosage of > or = 1 g/day affects the common cold. These studies have not found any consistent evidence that vitamin C supplementation reduces the incidence of the common cold in the general population. Nevertheless, in each of the 21 studies, vitamin C reduced the duration of episodes and the severity o...

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Scand J Infect Dis 26: 1-6, 1994

Since 1971, 21 placebo-controlled studies have been made to establish whether vitamin C at a dosage of ≥ 1 g/day affects the common cold. These studies have not found any consistent evidence that vitamin C supplementation reduces the incidence of the common cold in the general population. Nevertheless, in each of the 21 studies, vitamin C reduced the duration of episodes and the severity of the...

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Review Article

In 1975 Thomas Chalmers analyzed the possible effect of vitamin C on the common cold by calculating the average difference in the duration of cold episodes in vitamin C and control groups in seven placebo-controlled studies. He found that episodes were 0.11 ± 0.24 (SE) days shorter in the vitamin C groups and concluded that there was no valid evidence to indicate that vitamin C is beneficial in...

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تاریخ انتشار 2001